What is Keratoprosthesis ?

Boston Keratoprosthesis is an artificial cornea device which can be used in cases with severe corneal disease.
Most cases with corneal disease can be successfully managed with corneal transplantation surgery using corneal
tissue from human donors. However in certain situations routine corneal transplantation is not possible or carries a
greater risk of failure. Boston Keratoprosthesis can be used is such situations, wherein standard corneal
transplant has failed or is unlikely to succeed.

Boston Keratoprosthesis received US FDA approval in 1992, and is currently the most frequently used keratoprosthesis in United States. This device is made of polymethylmethacrylate (PMMA) which is a clear biocompatible plastic material with excellent optical properties. It consists of two parts but when fully assembled, it has the shape of a collar button

Indications that a patient is suitable for the Boston Keratoprosthesis include
 

• One or two failed corneal grafts, with poor prognosis for further grafting

 

• Vision less than 3/60 (20/400) in the affected eye & additionally with lower than optimal vision in the fellow eye

 

• No end stage glaucoma or retinal detachment

Prior to surgery, a detailed history will be taken which helps to assess the corneal condition and determine if the patient
is a good candidate for the surgery.

The one step surgery is relatively simple. General anesthesia is recommended. The device is incorporated into the
corneal graft, which is then sutured into the patient’s cornea like a standard graft. Visual improvement is usually already
seen the following day.


The Boston Keratoprosthesis is known for long term stability and safety. Its optical system can provide excellent vision if
the rest of the eye is undamaged.

Artificial cornea(Keratoprosthesis)